Krauth-Siegel, R. Luise: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

1

Evaluation of dipeptide nitriles as inhibitors of rhodesain, a major cysteine protease of Trypanosoma brucei

Schirmeister, Tanja, Schmitz, Janina, Jung, Sascha, Schmenger, Torsten, Luise Krauth-Siegel, R., Gütschow, Michael

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 666 KB

english, 2016

2

Parasite-specific trypanothione reductase as a drug target molecule

R. Luise Krauth-Siegel, Oliver Inhoff

Journal:

Parasitology Research

Year:

2003

Language:

english

File:

PDF, 326 KB

english, 2003

3

Dithiol Proteins as Guardians of the Intracellular Redox Milieu in Parasites: Old and New Drug Targets in Trypanosomes and Malaria-Causing Plasmodia

R. Luise Krauth-Siegel, Holger Bauer, R. Heiner Schirmer

Journal:

Year:

2005

File:

PDF, 8 KB

2005

4

Lipoamide dehydrogenase is essential for both bloodstream and procyclic Trypanosoma brucei

Angela Roldán, Marcelo A. Comini, Martina Crispo, R. Luise Krauth-Siegel

Journal:

Molecular Microbiology

Year:

2011

Language:

english

File:

PDF, 1.19 MB

english, 2011

5

Reduction of dehydroascorbate by trypanothione

R.Luise Krauth-Siegel, Heike Lüdemann

Journal:

Molecular and Biochemical Parasitology

Year:

1996

Language:

english

File:

PDF, 542 KB

english, 1996

6

Silencing of the thioredoxin gene in Trypanosoma brucei brucei

Armin Schmidt, Christine E. Clayton, R.Luise Krauth-Siegel

Journal:

Molecular and Biochemical Parasitology

Year:

2002

Language:

english

File:

PDF, 171 KB

english, 2002

7

FAD analogues as prosthetic groups of human glutathione reductase : Properties of the modified enzyme species and comparisons with the active site structure

R. Luise KRAUTH-SIEGEL, R. Heiner SCHIRMER, Sandro GHISLA

Journal:

Year:

1985

Language:

english

File:

PDF, 1015 KB

english, 1985

8

Glyoxalase II of African Trypanosomes Is Trypanothione-dependent

Irsch, Thorsten, Krauth-Siegel, R. Luise

Journal:

Journal of Biological Chemistry

Year:

2004

Language:

english

File:

PDF, 263 KB

english, 2004

9

Privileged structure-guided synthesis of quinazoline derivatives as inhibitors of trypanothione reductase

Andrea Cavalli, Federica Lizzi, Salvatore Bongarzone, Reto Brun, R. Luise Krauth-Siegel, Maria Laura Bolognesi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 362 KB

english, 2009

10

Thiol-based redox metabolism of protozoan parasites

Sylke Müller, Eva Liebau, Rolf D. Walter, R.Luise Krauth-Siegel

Journal:

Trends in Parasitology

Year:

2003

Language:

english

File:

PDF, 396 KB

english, 2003

11

Conjugation of Quinones with Natural Polyamines: Toward an Expanded Antitrypanosomatid Profile

Lizzi, Federica, Veronesi, Giacomo, Belluti, Federica, Bergamini, Christian, López-Sánchez, Almudena, Kaiser, Marcel, Brun, Reto, Krauth-Siegel, R. Luise, Hall, Dennis G., Rivas, Luis, Bolognesi, Mari

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 2.55 MB

english, 2012

12

Molecular interaction of artemisinin with translationally controlled tumor protein (TCTP) of Plasmodium falciparum

Tolga Eichhorn, Dominic Winter, Berthold Büchele, Natalie Dirdjaja, Martin Frank, Wolf-Dieter Lehmann, Rolf Mertens, R. Luise Krauth-Siegel, Thomas Simmet, Joachim Granzin, Thomas Efferth

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.28 MB

english, 2013

13

Inhibitor-induced dimerization of an essential oxidoreductase from African Trypanosomes

Wagner, Annika, Le, Thien Anh, Brennich, Martha, Klein, Philipp, Bader, Nicole, Diehl, Erika, Paszek, Daniel, Weickhmann, A. Katharina, Dirdjaja, Natalie, Krauth-Siegel, R. Luise, Engels, Bernd, Opatz

Journal:

Angewandte Chemie International Edition

Year:

2019

Language:

english

File:

PDF, 1.14 MB

english, 2019

14

Cytotoxic interactions of methylene blue with trypanosomatid-specific disulfide reductases and their dithiol products

Kathrin Buchholz, Marcelo A. Comini, Dirk Wissenbach, R. Heiner Schirmer, R. Luise Krauth-Siegel, Stephan Gromer

Journal:

Molecular and Biochemical Parasitology

Year:

2008

Language:

english

File:

PDF, 262 KB

english, 2008

15

Redox control in trypanosomatids, parasitic protozoa with trypanothione-based thiol metabolism

R. Luise Krauth-Siegel, Marcelo A. Comini

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2008

Language:

english

File:

PDF, 699 KB

english, 2008

16

Stress-Induced Protein S -Glutathionylation and S -Trypanothionylation in African Trypanosomes—A Quantitative Redox Proteome and Thiol Analysis

Ulrich, Kathrin, Finkenzeller, Caroline, Merker, Sabine, Rojas, Federico, Matthews, Keith, Ruppert, Thomas, Krauth-Siegel, R. Luise

Journal:

Antioxidants & Redox Signaling

Year:

2017

Language:

english

File:

PDF, 1.54 MB

english, 2017

17

Inhibitoren von Disulfid-Reduktasen als Chemotherapeutica – Design von Wirkstoffen gegen die Chagas-Krankheit und gegen die Malaria

Prof. Dr. R. Heiner Schirmer, Dr. Joachim G. Müller, Priv.-Doz. Dr. R. Luise Krauth-Siegel

Journal:

Angewandte Chemie

Year:

1995

Language:

german

File:

PDF, 1.66 MB

german, 1995

18

Unusually Bridged Tungsten Complexes with W(ER)2W(ER)3W Skeleton (ES or Se; R C2H5, n-C4H9, or C6H5)

Dipl.-Chem. Luise R. Krauth-Siegel, Dipl.-Chem. Wolfgang Schulze, Prof. Dr. Manfred L. Ziegler

Journal:

Angewandte Chemie International Edition

Year:

1980

Language:

english

File:

PDF, 241 KB

english, 1980

19

Synthesis, Inhibition Potency, Binding Mode, and Antiprotozoal Activities of Fluorescent Inhibitors of Trypanothione Reductase Based on Mepacrine-Conjugated Diaryl Sulfide Scaffolds

Christian Eberle, Johannes A. Burkhard, Bernhard Stump, Marcel Kaiser, Reto Brun, R. Luise Krauth-Siegel, François Diederich

Journal:

Year:

2009

Language:

english

File:

PDF, 555 KB

english, 2009

20

Inside Cover: Synthesis, Inhibition Potency, Binding Mode, and Antiprotozoal Activities of Fluorescent Inhibitors of Trypanothione Reductase Based on Mepacrine-Conjugated Diaryl Sulfide Scaffolds (ChemMedChem 12/2009)

Christian Eberle, Johannes A. Burkhard, Bernhard Stump, Marcel Kaiser, Reto Brun, R. Luise Krauth-Siegel, François Diederich

Journal:

Year:

2009

File:

PDF, 467 KB

2009

21

Preparative enzymatic synthesis of trypanothione and trypanothione analogues

Marcelo A. Comini, Natalie Dirdjaja, Mariel Kaschel, R. Luise Krauth-Siegel

Journal:

International Journal for Parasitology

Year:

2009

Language:

english

File:

PDF, 216 KB

english, 2009

22

Enzymatic reduction studies of nitroheterocycles

Cécile Viodé, Nadir Bettache, Narimantas Cenas, R.Luise Krauth-Siegel, Gérard Chauvière, Norbert Bakalara, Jacques Périé

Journal:

Biochemical Pharmacology

Year:

1999

Language:

english

File:

PDF, 319 KB

english, 1999

23

Disulfide-Reductase Inhibitors as Chemotherapeutic Agents: The Design of Drugs for Trypanosomiasis and Malaria

Prof. Dr. R. Heiner Schirmer, Dr. Joachim G. Müller, Priv.-Doz. R. Luise Krauth-Siegel

Journal:

Angewandte Chemie International Edition

Year:

1995

Language:

english

File:

PDF, 1.68 MB

english, 1995

24

Glutathione Reductase from Human Erythrocytes : Amino-Acid Sequence of the Structurally Known FAD-Binding Domain

Renate UNTUCHT-GRAU, R. Heiner SCHIRMER, Ilse SCHIRMER, R. Luise KRAUTH-SIEGEL

Journal:

Year:

1981

Language:

english

File:

PDF, 1.08 MB

english, 1981

25

Synthesis and in vitro antikinetoplastid activity of polyamine-hydroxybenzotriazole conjugates

Jagu, Elodie, Pomel, Sébastien, Diez-Martinez, Alba, Ramiandrasoa, Florence, Luise Krauth-Siegel, R., Pethe, Stéphanie, Blonski, Casimir, Labruère, Raphaël, Loiseau, Philippe M.

Journal:

Bioorganic & Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 565 KB

english, 2016

26

Biological Evaluation and X-ray Co-crystal Structures of Cyclohexylpyrrolidine Ligands for Trypanothione Reductase, an Enzyme from the Redox Metabolism of Trypanosoma

De Gasparo, Raoul, Brodbeck-Persch, Elke, Bryson, Steve, Hentzen, Nina B., Kaiser, Marcel, Pai, Emil F., Krauth-Siegel, R. Luise, Diederich, François

Journal:

Year:

2018

Language:

english

File:

PDF, 1.45 MB

english, 2018

27

Interaction of a glutathione S-conjugate with glutathione reductase Kinetic and X-ray crystallographic studies

Manfred BILZER, R. Luise KRAUTH-SIEGEL, R. Heiner SCHIRMER, Theo P. M. AKERBOOM, Helmut SIES, Georg E. SCHULZ

Journal:

Year:

1984

Language:

english

File:

PDF, 578 KB

english, 1984

28

Structure of thioredoxin from Trypanosoma brucei brucei

Rosmarie Friemann, Heide Schmidt, S. Ramaswamy, Michael Forstner, R.Luise Krauth-Siegel, Hans Eklund

Journal:

Year:

2003

Language:

english

File:

PDF, 327 KB

english, 2003

29

Glutaredoxin-deficiency confers bloodstream Trypanosoma brucei with improved thermotolerance

Musunda, Blessing, Benítez, Diego, Dirdjaja, Natalie, Comini, Marcelo A., Krauth-Siegel, R. Luise

Journal:

Molecular and Biochemical Parasitology

Year:

2015

Language:

english

File:

PDF, 2.39 MB

english, 2015

30

Low-Molecular-Mass Antioxidants in Parasites

Krauth-Siegel, R. Luise, Leroux, Alejandro E.

Journal:

Antioxidants & Redox Signaling

Year:

2012

Language:

english

File:

PDF, 701 KB

english, 2012

31

Trypanosoma brucei tryparedoxin, a thioredoxin-like protein in African trypanosomes

Heike Lüdemann, Matthias Dormeyer, Christian Sticherling, Dirk Stallmann, Hartmut Follmann, R.Luise Krauth-Siegel

Journal:

Year:

1998

Language:

english

File:

PDF, 279 KB

english, 1998

32

Inhibition of Trypanosoma cruzi Trypanothione Reductase by Acridines: Kinetic Studies and Structure−Activity Relationships

Bonse, Susanne, Santelli-Rouvier, Christiane, Barbe, Jacques, Krauth-Siegel, R. Luise

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 170 KB

english, 1999

33

(2,2‘:6‘,2‘ ‘-Terpyridine)platinum(II) Complexes Are Irreversible Inhibitors of Trypanosoma c ruzi Trypanothione Reductase But Not of Human Glutathione Reductase

Bonse, Susanne, Richards, Jonathan M., Ross, Steven A., Lowe, Gordon, Krauth-Siegel, R. Luise

Journal:

Journal of Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 178 KB

english, 2000

34

The silicon trypanosome

BAKKER, BARBARA M., KRAUTH-SIEGEL, R. LUISE, CLAYTON, CHRISTINE, MATTHEWS, KEITH, GIROLAMI, MARK, WESTERHOFF, HANS V., MICHELS, PAUL A. M., BREITLING, RAINER, BARRETT, MICHAEL P.

Journal:

Year:

2010

Language:

english

File:

PDF, 205 KB

english, 2010

35

Depletion of the thioredoxin homologue tryparedoxin impairs antioxidative defence in African trypanosomes

Comini, Marcelo A., Krauth-Siegel, R. Luise, Flohé, Leopold

Journal:

Biochemical Journal

Year:

2007

Language:

english

File:

PDF, 482 KB

english, 2007

36

Crystal structure of theTrypanosoma cruzi trypanothione reductase·mepacrine complex

Jacoby, Elke M., Schlichting, Ilme, Lantwin, Christina B., Kabsch, Wolfgang, Krauth-Siegel, R. Luise

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1996

Language:

english

File:

PDF, 816 KB

english, 1996

37

The mitochondrial peroxiredoxin displays distinct roles in different developmental stages of African trypanosomes

Bogacz, Marta, Dirdjaja, Natalie, Wimmer, Benedikt, Habich, Carina, Krauth-Siegel, R. Luise

Journal:

Year:

2020

File:

PDF, 3.41 MB

2020

38

Dithiolproteine als Hüter des intrazellulären Redoxmilieus bei Parasiten: alte und neue Wirkstoff-Targets bei Trypanosomiasis und Malaria

R. Luise Krauth-Siegel, Holger Bauer, R. Heiner Schirmer

Journal:

Angewandte Chemie

Year:

2005

Language:

german

File:

PDF, 866 KB

german, 2005

39

Cloning, functional analysis, and mitochondrial localization of Trypanosoma brucei monothiol glutaredoxin-1

Filser, Michael, Comini, Marcelo A., Molina-Navarro, Maria M., Dirdjaja, Natalie, Herrero, Enrique, Krauth-Siegel, R. Luise

Journal:

Biological Chemistry

Year:

2008

Language:

english

File:

PDF, 415 KB

english, 2008

40

Coupling of a Competitive and an Irreversible Ligand Generates Mixed Type Inhibitors of Trypanosoma c ruzi Trypanothione Reductase

Inhoff, Oliver, Richards, Jonathan M., Brîet, Jan Willem, Lowe, Gordon, Krauth-Siegel, R. Luise

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 192 KB

english, 2002

41

Inhibition of human glutathione reductase by the nitrosourea drugs 1,3-bis(2-chloroethyl)-1-nitrosourea and 1-(2-chloroethyl)-3-(2-hydroxyethyl)-1-nitrosourea : A crystallographic analysis

P. Andrew KARPLUS, R. Luise KRAUTH-SIEGEL, R. Heiner SCHIRMER, Georg E. SCHULZ

Journal:

Year:

1988

Language:

english

File:

PDF, 592 KB

english, 1988

42

Glutathione Reductase Turned into Trypanothione Reductase: Structural Analysis of an Engineered Change in Substrate Specificity †,‡

Stoll, Vincent S., Simpson, Sarah J., Krauth-Siegel, R. Luise, Walsh, Christopher T., Pai, Emil F.

Journal:

Year:

1997

Language:

english

File:

PDF, 271 KB

english, 1997

43

Inhibitor-induced dimerization of an essential oxidoreductase from African Trypanosomes

Wagner, Annika, Le, Thien Anh, Brennich, Martha, Klein, Philipp, Bader, Nicole, Diehl, Erika, Paszek, Daniel, Weickhmann, A. Katharina, Dirdjaja, Natalie, Krauth-Siegel, R. Luise, Engels, Bernd, Opatz

Journal:

Angewandte Chemie

Year:

2019

Language:

english

File:

PDF, 1.14 MB

english, 2019

44

Pentafluorosulfanyl as a Novel Building Block for Enzyme Inhibitors: Trypanothione Reductase Inhibition and Antiprotozoal Activities of Diarylamines

Bernhard Stump, Christian Eberle, W. Bernd Schweizer, Marcel Kaiser, Reto Brun, R. Luise Krauth-Siegel, Dieter Lentz, François Diederich

Journal:

Year:

2009

Language:

english

File:

PDF, 516 KB

english, 2009

45

Mitochondrial adenylate kinase (AK2) from bovine heart : The complete primary structure

Rainer FRANK, Marcus TROSIN, Alfredo G. TOMASSELLI, Lafayette NODA, R. Luise KRAUTH-SIEGEL, R. Heiner SCHIRMER

Journal:

Year:

1986

Language:

english

File:

PDF, 579 KB

english, 1986

46

Toward the Development of Dual-Targeted Glyceraldehyde-3-phosphate Dehydrogenase/Trypanothione Reductase Inhibitors against Trypanosoma brucei and Trypanosoma cruzi

Belluti, Federica, Uliassi, Elisa, Veronesi, Giacomo, Bergamini, Christian, Kaiser, Marcel, Brun, Reto, Viola, Angelo, Fato, Romana, Michels, Paul A. M., Krauth-Siegel, R. Luise, Cavalli, Andrea, Bolo

Journal:

Year:

2014

Language:

english

File:

PDF, 1.21 MB

english, 2014

47

1H,13C, and15N assignment of the oxidized and reduced forms ofT. bruceiglutathione peroxidase-type tryparedoxin peroxidase

Johannes Melchers, Luise Krauth-Siegel, Claudia Muhle-Goll

Journal:

Biomolecular NMR Assignments

Year:

2008

Language:

english

File:

PDF, 374 KB

english, 2008

48

The conserved Cys76 plays a crucial role for the conformation of reduced glutathione peroxidase-type tryparedoxin peroxidase

Claudia Muhle-Goll, Florian Füller, Anne S. Ulrich, R. Luise Krauth-Siegel

Journal:

Year:

2010

Language:

english

File:

PDF, 655 KB

english, 2010

49

Growth inhibition of bloodstream forms of Trypanosoma brucei by the iron chelator deferoxamine

Tanja Breidbach, Stefan Scory, R.Luise Krauth-Siegel, Dietmar Steverding

Journal:

International Journal for Parasitology

Year:

2002

Language:

english

File:

PDF, 217 KB

english, 2002

50

Nitrofuran drugs as common subversive substrates of Trypanosoma cruzi lipoamide dehydrogenase and trypanothione reductase

Klaus Blumenstiel, Ralf Schöneck, Vanessa Yardley, Simon L. Croft, R.Luise Krauth-Siegel

Journal:

Biochemical Pharmacology

Year:

1999

Language:

english

File:

PDF, 318 KB

english, 1999

To build up a library is to create a life. It’s never just a random collection of books.

— Carlos María Domínguez

Official channel

Z-Library Desktop Launcher

Z-Library Since 2009 support@1delivery.pm

EnglishРусскийEspañolItalianoελληνικάاللغة العربيةBahasa IndonesiaBahasa Malaysiaहिन्दीDeutschFrançaisPortuguêsУкраїнськаPolski中文繁體中文日本語Tiếng ViệtAzərbaycan DiliՀայոց լեզուภาษาไทยTürk Diliქართველიবাংলাپښتوతెలుగుاردو한국어SrpskiБългарски